Tuesday, June 12, 2018

Focal Cortical Dysplasia Findings

A colleague of mine has just had a new article published in the journal Brain Research (I'm third author on this paper). The study looks at patients with Focal Cortical Dysplasia, a medical condition that predisposes the patient to developing epilepsy. Our work looked at a large collection of brain MRI examinations of patients with Focal Cortical Dysplasia and compared them with a pool of typically developing participants.



Our findings demonstrate hemispheric asymmetries in Focal Cortical Dysplasia patients focused on the thalamus and assessed with diffusion tractography (which makes very pretty pictures like the one below which came from the paper).

Here is a pretty picture from our article:


These thalamic asymmetries are based on reductions of the volume of the thalamus located in the same hemisphere as the Focal Cortical Dysplasia.

 For a LOT more detail, check out the original manuscript here.